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236,237 In addition, NF-κB-deficient mice have been reported to be more prone to sepsis, 238 hence complications such as immunosuppression and infection susceptibility caused by long-term NF-κB inhibition must be considered (Table 4)

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Laboratory studies suggest that GSH may help reduce tyrosinase activity while encouraging the production of relatively more pheomelanin, the lighter form of melanin, compared with eumelanin, the darker pigment