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30, 31 The development of these symptoms could thus prompt an increased prescription or self-administration of vitamin supplements, especially in more health-conscious populations such as the NHS and HPFS in which the use of supplements is higher than in the general US population
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Because ONL belongs to the photoreceptor cell layer, it often experiences a decrease in thickness and a decrease in the number of rod and cone cells when damaged, leading to problems such as decreased visual sensitivity, loss of field of view, and color vision abnormalities (Shang et al., 2014)