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Trientine diHClide is another common copper chelator used for treating Wilson's disease (132), which can selectively bind Cu 2+ ions to improve mitochondrial function in patients with hypertrophic cardiomyopathy (73), as well as restore mitochondrial function and normalize myocardial expression and enzymatic activity of proteins involved in energy metabolism among diabetic patients (133)
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The role of lipid peroxidation in ferroptosis Lipid metabolism is also closely related to ferroptosis
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