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This process is self-reinforcing: inflammation-derived oxidative stress promotes further ferroptosis, while dying ferroptotic cells release DAMPs that activate surrounding structural and immune cells, intensifying the inflammatory response ( 6.2 Classical and non-classical pathways of ferroptosis regulation The regulation of ferroptosis in the asthmatic airway involves both canonical and alternative mechanisms that determine cellular susceptibility to this form of cell death
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Tran HT, Elamin Y, Simon GR, Blumenschein GR , Tsao AS, Papadimitrakopoulou, V, Gibbons DL, Fossella FV, Lanman RB, Banks KC, Byers LA, Zhang J, Heymach J
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