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For the same 220-pound person, 22.5% means losing roughly 50 pounds, nearly 17 more pounds than semaglutide would produce on average

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Thus, it is critical to determine the detailed mechanism of action of the intervention and confirm that it does not reduce the extent of injury, which would then indirectly result in a robust regenerative response, which may not be relevant in the clinic when the patient is treated in a delayed fashion