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Some identified metabolites are related to the Warburg effect and glutaminolysis, processes which exclusively occur during tumorigenesis, and which are considered a unique feature of thyroid carcinogenesis ( Obtaining the comprehensive metabolic panel of patients with thyroid nodules could improve the understanding of molecular pathogenesis of thyroid nodules and lead to solving the indeterminate sample problem, through the discovery of new metabolic biomarkers

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It is not genetically manipulated