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Abbreviations : PH Pulmonary hypertension, MI Myocardial Infarction, GPX4 Glutathione Peroxidase 4, SLC7A11 Solute Carrier Family 7 Member 11, NRF2 Nuclear factor erythroid2-related factor 2, AMPK AMP-activated protein kinase, SIRT1 Sirtuin 1, GSH Glutathione, FXN Iron-sulfur cluster biogenesis protein Frataxin, ROS Reactive oxygen species, HO-1 Heme oxygenase-1, GSK3β Glycogen synthase kinase-3, AKT Protein kinase Myocardial infarction MI culminates in cardiac detriment precipitated by cellular death and inadequate self-regeneration of cardiomyocytes [596]
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With thousands now accessing these drugs via private clinics or online providers, often without in-person follow-up, questions about their impact on fertility and pregnancy are becoming more urgent
