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52 Vitamin B12 Deficiency in Elderly and Diabetics Vitamin B12 deficiency is common in old age which is mainly attributed to decreased absorption of vitamin B12 (pernicious anaemia, atrophic gastritis), 53 malnutrition, strict vegeterians 54 or due to increased urinary and gut loss of vitamin B12 55 or through age-related defects in the megalin-cubulin-amnionless complex of receptors which play a pivotal role in absorption of vitamin B12