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hEDS patients experience orthostatic intolerance and bladder, gastrointestinal, secretomotor, and pupillomotor complaints.9, 10, 11 Underlying cardiovascular autonomic manifestations of hEDS are postural tachycardia syndrome (POTS), neuro-cardiogenic syncope, and orthostatic hypotension

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FOXO4 in Cellular Aging and Senescence Regulation