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While ergothioneine has been demonstrated to be protective in a number of other in vivo models of liver injury (Reference Tang, Masuo and Sakai46,Reference Salama and Omar66,Reference Kawano, Cho and Haruna95,Reference Deiana, Rosa and Casu96) , including the aforementioned model of diabetic liver damage (Reference Dare, Channa and Nadar91)

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We aim to mimic the role of natural hormones by supplementing their declining levels