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Lane notes

Duotone aurora — cool blue brief on the left, soft violet sheet on the right for cargo details.

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Microglia in PD exhibit a chronic pro-inflammatory phenotype (M1 state), releasing TNF-α, IL-1β, and reactive oxygen species (ROS) that exacerbate neurodegeneration in the SNpc

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The lack of CYP2E1 has an impact over ethanol-induced sensitization and on voluntary ethanol preference in knockout CYP2E1 mice after repeated intermittent alcohol intake showed a reduction in preference for ethanol intake compared with wild-type mice [146]

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