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doi: 10.3389/fpls.2022.802274 46 IshfaqM.ZhongY.WangY.LiX

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Further, microglial activation appears to require alpha-synuclein phagocytosis and NADPH oxidase activation, since knocking down this enzyme results in attenuated ROS release from microglia and protects dopaminergic neurons in primary mesencephalic neuron-glia co-cultures when challenged with alpha-synuclein [276]

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